Including files on NFS mount slow with APC enabled

I am struggling with the performance of some websites that use a lot of includes (using include_once). The files are on a NFS mount (NFSv4), and I use APC to speed things up. APC has enough memory, and I see all included files are in the APC cache. apc.include_once_override is enabled. This is on a Ubuntu Linux 10.04 server. What surprises me is that using strace I see apache open()ing all included files. I would think this is not necessary as APC has these files in its cache. Opening a file takes 1-3 ms, the websites include 100-200 files, so this costs about half a second for each request. I tried a lot to prevent this but my options are exhausted. Is it normal that all these files are open()ed each time, and if so how can I speed up these includes? Part of the trace is below, look especially at the first line where 2ms are lost while this file is in the APC cache: open("/[removed]/library/Zend/Application.php", O_RDONLY) = 1440 <0.002035> fstat(1440, {st_mode=S_IFREG|0755, st_size=11365, ...}) = 0 <0.000137> fstat(1440, {st_mode=S_IFREG|0755, st_size=11365, ...}) = 0 <0.000124> fstat(1440, {st_mode=S_IFREG|0755, st_size=11365, ...}) = 0 <0.000133> mmap(NULL, 11365, PROT_READ, MAP_SHARED, 1440, 0) = 0x7faf3f068000 <0.000395> stat("/[removed]/library/Zend/Application.php", {st_mode=S_IFREG|0755, st_size=11365, ...}) = 0 <0.000219> munmap(0x7faf3f068000, 11365) = 0 <0.000151> close(1440) = 0 <0.000845> Thanks, Mark