Massive amounts of data to SQL

Hi everyone, I know this is a relatively simple question, but what would be the most efficient way of entering the contents of a large form (nearly 400 fields) into a MySQL database? Every day the form must be able Please provide an example script that I can use to refer to if you have time. Or show me a page that has a tutorial for a similar task. Thankyou very much for your help! Liam